STRINGSTRING
HMPREF9018_1977 protein (Prevotella amnii) - STRING interaction network
"HMPREF9018_1977" - DnaJ domain protein in Prevotella amnii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMPREF9018_1977DnaJ domain protein (278 aa)    
Predicted Functional Partners:
dnaK
Heat shock protein 70 ; Acts as a chaperone (633 aa)
   
  0.956
HMPREF9018_0795
DnaJ domain protein (234 aa)
 
 
  0.752
grpE
HSP-70 cofactor ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depend [...] (201 aa)
     
 
  0.727
atpD
F-ATPase subunit beta ; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (508 aa)
       
    0.696
atpA
F-ATPase subunit alpha ; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (527 aa)
       
    0.696
ftsH
ATP-dependent zinc metalloprotease FtsH ; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (692 aa)
     
 
    0.696
HMPREF9018_1978
Type I restriction enzyme HsdR protein N-terminal domain protein (148 aa)
 
          0.680
HMPREF9018_1214
Peptidase M16 inactive domain protein (984 aa)
   
 
    0.653
HMPREF9018_1100
Peptidase, M16 family (938 aa)
   
 
    0.653
HMPREF9018_1091
Peptidase M16 inactive domain protein (409 aa)
   
 
    0.653
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
Server load: low (8%) [HD]