STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureB2Urease alpha subunit; evidence=ISS; db_xref=bcenocepacia:CAL3106; date=20070321; method=automatic:reciprocal fasta; Duplicated gene in HMU03060; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (568 aa)    
Predicted Functional Partners:
ureA
Fusion of urease beta and gamma subunits; evidence=ISS; db_xref=scoelicolor:SCO5525; date=20070321; method=automatic:reciprocal fasta; In the C-terminal section; belongs to the urease beta subunit family.
 0.999
ureA2
Putative fusion of urease beta and gamma subunits; evidence=IEA; db_xref=scoelicolor:SCO5525; date=20070321; method=automatic:top fasta hit; Duplicated gene in HMU03050.
 0.999
ureF
Putative urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.966
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.953
HMU04840
Putative arginase; evidence=ISS; Belongs to the arginase family.
    
 0.930
ureE
Putative urease accesory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.912
ureB
Urease alpha subunit; evidence=ISS; db_xref=pmirabilis:PMI3685; date=20070321; method=automatic:reciprocal fasta.
  
  
 
0.901
ureH
Putative urease accessory protein UreH; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.885
hypB
Putative periplasmic cytochrome C, partial gene (pseudogene); PS00190 Cytochrome c family heme-binding site signature.
  
  
 0.712
flaA
Putative flagellin, FlaA; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
      
 0.592
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.