STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH59898.1COGs: COG1423 ATP-dependent DNA ligase homolog of eukaryotic ligase III; InterPro IPR012310:IPR001072; KEGG: mba:Mbar_A0970 hypothetical protein; PFAM: ATP dependent DNA ligase; SPTR: Q46DV0 Putative uncharacterized protein; manually curated; PFAM: ATP dependent DNA ligase domain; TIGRFAM: conserved hypothetical protein TIGR01209. (389 aa)    
Predicted Functional Partners:
AEH60260.1
Protein of unknown function UPF0278; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.813
AEH59899.1
COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644:IPR013785; KEGG: mbu:Mbur_1759 CBS domain-containing protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Q12V77 Cystathionine beta-synthase domain-containing protein; PFAM: CBS domain.
       0.743
AEH59900.1
COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644:IPR013785; KEGG: mac:MA4650 hypothetical protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Q8TH72 Putative uncharacterized protein; PFAM: CBS domain.
       0.621
AEH59897.1
COGs: COG3276 Selenocysteine-specific translation elongation factor; InterPro IPR009000:IPR004161; KEGG: mbu:Mbur_1757 elongation factor Tu domain-containing protein; PFAM: elongation factor Tu domain 2 protein; SPTR: Q12V79 Translation elongation factor SELB; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain.
       0.595
AEH59902.1
COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644:IPR013785; KEGG: mma:MM_1302 hypothetical protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Q8PXC0 Conserved protein; PFAM: CBS domain.
 
     0.565
AEH59901.1
Putative signal transduction protein with CBS domains; COGs: COG2524 transcriptional regulator protein; InterPro IPR000644:IPR013785; KEGG: mac:MA4649 hypothetical protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Q8TH73 Putative uncharacterized protein; PFAM: CBS domain.
       0.559
AEH60253.1
Protein of unknown function DUF166; COGs: COG1810 conserved hypothetical protein; InterPro IPR003745; KEGG: mba:Mbar_A1097 hypothetical protein; PFAM: Protein of unknown function DUF166; SPTR: Q46DH7 Putative uncharacterized protein; PFAM: Uncharacterized ArCR, COG1810.
  
     0.529
AEH61219.1
AAA ATPase central domain protein; COGs: COG1223 ATPase (AAA+ superfamily); InterPro IPR003960:IPR003959:IPR003593; KEGG: mbu:Mbur_2106 AAA ATPase; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: Q12U96 AAA ATPase; PFAM: ATPase family associated with various cellular activities (AAA); Belongs to the AAA ATPase family.
  
     0.519
AEH60103.1
COGs: COG0417 DNA polymerase elongation subunit (family B); InterProIPR017964:IPR006172:IPR012337:IPR006133:IPR 006134:IPR017966:IPR004578; KEGG: mbu:Mbur_1688 replicative DNA polymerase I; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase B; SPTR: Q12VE4 DNA polymerase; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: pentatricopeptide repeat domain (PPR motif); DNA polymerase (pol2).
 
    0.491
AEH61655.1
Protein of unknown function DUF166; COGs: COG1810 conserved hypothetical protein; InterPro IPR003745; KEGG: mba:Mbar_A2087 thymidylate synthase; PFAM: Protein of unknown function DUF166; SPTR: Q46AS4 Thymidylate synthase; PFAM: Uncharacterized ArCR, COG1810.
 
     0.491
Your Current Organism:
Methanosalsum zhilinae
NCBI taxonomy Id: 679901
Other names: M. zhilinae DSM 4017, Methanosalsum zhilinae DSM 4017, Methanosalsum zhilinae str. DSM 4017, Methanosalsum zhilinae strain DSM 4017
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