node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpet_0321 | Mpet_1351 | Mpet_0321 | Mpet_1351 | COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mhu:Mhun_2475 serine--glyoxylate transaminase; PFAM: aminotransferase class V; SPTR: L-aspartate aminotransferase / phosphoserine aminotransferase; PFAM: Aminotransferase class-V. | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.467 |
Mpet_0321 | Mpet_1356 | Mpet_0321 | Mpet_1356 | COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mhu:Mhun_2475 serine--glyoxylate transaminase; PFAM: aminotransferase class V; SPTR: L-aspartate aminotransferase / phosphoserine aminotransferase; PFAM: Aminotransferase class-V. | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Glycosyl transferase family 2. | 0.467 |
Mpet_0321 | ribH | Mpet_0321 | Mpet_0319 | COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mhu:Mhun_2475 serine--glyoxylate transaminase; PFAM: aminotransferase class V; SPTR: L-aspartate aminotransferase / phosphoserine aminotransferase; PFAM: Aminotransferase class-V. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.794 |
Mpet_0321 | ribL | Mpet_0321 | Mpet_0560 | COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mhu:Mhun_2475 serine--glyoxylate transaminase; PFAM: aminotransferase class V; SPTR: L-aspartate aminotransferase / phosphoserine aminotransferase; PFAM: Aminotransferase class-V. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.725 |
Mpet_0561 | ribK | Mpet_0561 | Mpet_0554 | Conserved hypothetical protein; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; KEGG: mbn:Mboo_0210 hypothetical protein; SPTR: Putative uncharacterized protein. | Transcriptional regulator, MarR family; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.594 |
Mpet_0561 | ribL | Mpet_0561 | Mpet_0560 | Conserved hypothetical protein; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; KEGG: mbn:Mboo_0210 hypothetical protein; SPTR: Putative uncharacterized protein. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.927 |
Mpet_0824 | ribL | Mpet_0824 | Mpet_0560 | Phosphatidate cytidylyltransferase; COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: mem:Memar_0524 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: CTP:2, 3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase; PFAM: Cytidylyltransferase family. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.610 |
Mpet_1351 | Mpet_0321 | Mpet_1351 | Mpet_0321 | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Putative uncharacterized protein. | COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mhu:Mhun_2475 serine--glyoxylate transaminase; PFAM: aminotransferase class V; SPTR: L-aspartate aminotransferase / phosphoserine aminotransferase; PFAM: Aminotransferase class-V. | 0.467 |
Mpet_1351 | Mpet_1355 | Mpet_1351 | Mpet_1355 | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Putative uncharacterized protein. | Glycosyl transferase family 2; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR001173; KEGG: mpd:MCP_0949 hypothetical protein; PFAM: glycosyl transferase family 2; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Putative uncharacterized protein; manually curated; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; Glycosyl transferase family 2; TIGRFAM: nucleotide sugar dehydrogenase. | 0.955 |
Mpet_1351 | ribL | Mpet_1351 | Mpet_0560 | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Putative uncharacterized protein. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.565 |
Mpet_1355 | Mpet_1351 | Mpet_1355 | Mpet_1351 | Glycosyl transferase family 2; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR001173; KEGG: mpd:MCP_0949 hypothetical protein; PFAM: glycosyl transferase family 2; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Putative uncharacterized protein; manually curated; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; Glycosyl transferase family 2; TIGRFAM: nucleotide sugar dehydrogenase. | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.955 |
Mpet_1355 | Mpet_1356 | Mpet_1355 | Mpet_1356 | Glycosyl transferase family 2; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR001173; KEGG: mpd:MCP_0949 hypothetical protein; PFAM: glycosyl transferase family 2; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Putative uncharacterized protein; manually curated; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; Glycosyl transferase family 2; TIGRFAM: nucleotide sugar dehydrogenase. | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Glycosyl transferase family 2. | 0.989 |
Mpet_1355 | ribL | Mpet_1355 | Mpet_0560 | Glycosyl transferase family 2; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR001173; KEGG: mpd:MCP_0949 hypothetical protein; PFAM: glycosyl transferase family 2; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Putative uncharacterized protein; manually curated; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; Glycosyl transferase family 2; TIGRFAM: nucleotide sugar dehydrogenase. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.667 |
Mpet_1356 | Mpet_0321 | Mpet_1356 | Mpet_0321 | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Glycosyl transferase family 2. | COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mhu:Mhun_2475 serine--glyoxylate transaminase; PFAM: aminotransferase class V; SPTR: L-aspartate aminotransferase / phosphoserine aminotransferase; PFAM: Aminotransferase class-V. | 0.467 |
Mpet_1356 | Mpet_1355 | Mpet_1356 | Mpet_1355 | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Glycosyl transferase family 2. | Glycosyl transferase family 2; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR001173; KEGG: mpd:MCP_0949 hypothetical protein; PFAM: glycosyl transferase family 2; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Putative uncharacterized protein; manually curated; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; Glycosyl transferase family 2; TIGRFAM: nucleotide sugar dehydrogenase. | 0.989 |
Mpet_1356 | ribL | Mpet_1356 | Mpet_0560 | KEGG: mpd:MCP_0952 hypothetical protein; SPTR: Glycosyl transferase family 2. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.565 |
Mpet_1381 | ribH | Mpet_1381 | Mpet_0319 | PfkB domain protein; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611; KEGG: tye:THEYE_A1795 RfaE bifunctional protein, domain I; PFAM: PfkB domain protein; SPTR: RfaE bifunctional protein, domain I; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.617 |
Mpet_1381 | ribL | Mpet_1381 | Mpet_0560 | PfkB domain protein; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611; KEGG: tye:THEYE_A1795 RfaE bifunctional protein, domain I; PFAM: PfkB domain protein; SPTR: RfaE bifunctional protein, domain I; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.727 |
Mpet_2012 | ribK | Mpet_2012 | Mpet_0554 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: mem:Memar_0857 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | Transcriptional regulator, MarR family; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.900 |
Mpet_2012 | ribL | Mpet_2012 | Mpet_0560 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: mem:Memar_0857 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.903 |