node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpet_0083 | guaAB | Mpet_0083 | Mpet_2387 | COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426:IPR017932:IPR000583:IPR001962; KEGG: mem:Memar_2057 asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.901 |
Mpet_0083 | pyrG | Mpet_0083 | Mpet_2388 | COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426:IPR017932:IPR000583:IPR001962; KEGG: mem:Memar_2057 asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.943 |
Mpet_0677 | dcd | Mpet_0677 | Mpet_1945 | COGs: COG0717 Deoxycytidine deaminase; InterPro IPR008180:IPR011962; KEGG: mem:Memar_0554 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; SPTR: dCTP deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: dUTPase; TIGRFAM: deoxycytidine triphosphate deaminase. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.916 |
Mpet_0677 | ndk | Mpet_0677 | Mpet_2107 | COGs: COG0717 Deoxycytidine deaminase; InterPro IPR008180:IPR011962; KEGG: mem:Memar_0554 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; SPTR: dCTP deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: dUTPase; TIGRFAM: deoxycytidine triphosphate deaminase. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.938 |
Mpet_0677 | pyrG | Mpet_0677 | Mpet_2388 | COGs: COG0717 Deoxycytidine deaminase; InterPro IPR008180:IPR011962; KEGG: mem:Memar_0554 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; SPTR: dCTP deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: dUTPase; TIGRFAM: deoxycytidine triphosphate deaminase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.947 |
dcd | Mpet_0677 | Mpet_1945 | Mpet_0677 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | COGs: COG0717 Deoxycytidine deaminase; InterPro IPR008180:IPR011962; KEGG: mem:Memar_0554 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; SPTR: dCTP deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: dUTPase; TIGRFAM: deoxycytidine triphosphate deaminase. | 0.916 |
dcd | ndk | Mpet_1945 | Mpet_2107 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.938 |
dcd | pyrG | Mpet_1945 | Mpet_2388 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.940 |
guaAB | Mpet_0083 | Mpet_2387 | Mpet_0083 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426:IPR017932:IPR000583:IPR001962; KEGG: mem:Memar_2057 asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). | 0.901 |
guaAB | ndk | Mpet_2387 | Mpet_2107 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.584 |
guaAB | pyrG | Mpet_2387 | Mpet_2388 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.987 |
guaAB | rpl10 | Mpet_2387 | Mpet_2126 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.675 |
guaAB | rpl11 | Mpet_2387 | Mpet_2128 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.691 |
guaAB | rpl13 | Mpet_2387 | Mpet_0753 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.713 |
guaAB | rpl5 | Mpet_2387 | Mpet_2201 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.432 |
ndk | Mpet_0677 | Mpet_2107 | Mpet_0677 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | COGs: COG0717 Deoxycytidine deaminase; InterPro IPR008180:IPR011962; KEGG: mem:Memar_0554 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; SPTR: dCTP deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: dUTPase; TIGRFAM: deoxycytidine triphosphate deaminase. | 0.938 |
ndk | dcd | Mpet_2107 | Mpet_1945 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.938 |
ndk | guaAB | Mpet_2107 | Mpet_2387 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.584 |
ndk | pyrG | Mpet_2107 | Mpet_2388 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.957 |
ndk | rpl10 | Mpet_2107 | Mpet_2126 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.716 |