STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (284 aa)    
Predicted Functional Partners:
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 0.997
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.962
Bcop_0740
KEGG: bfs:BF0897 putative transmembrane protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504106428.
       0.732
Bcop_0742
Dipeptidyl-peptidase IV; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469:IPR001375; KEGG: bfs:BF0899 putative dipeptidyl peptidase; PFAM: Peptidase S9B, dipeptidylpeptidase IV N-terminal; Peptidase S9, prolyl oligopeptidase, catalytic domain; PRIAM: Dipeptidyl-peptidase IV; SPTR: Dipeptidyl peptidase IV; IMG reference gene:2504106430; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region.
       0.715
Bcop_0400
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: bfs:BF0023 putative dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Putative dihydrolipoamide dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504106063; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation d [...]
 
  
 0.612
Bcop_1354
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 
    0.563
Bcop_1299
COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR003437:IPR020580; KEGG: bfs:BF2079 glycine dehydrogenase; PFAM: Glycine cleavage system P-protein, N-terminal; SPTR: Glycine dehydrogenase [decarboxylating]; TIGRFAM: Glycine cleavage system P protein, homodimeric; IMG reference gene:2504107006; PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); Belongs to the GcvP family.
  
  
 0.552
Bcop_0743
Conserved hypothetical protein CHP01212; COGs: COG1242 Fe-S oxidoreductase; InterPro IPR007197:IPR006638:IPR005911; KEGG: bfr:BF0982 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01212; IMG reference gene:2504106431; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family.
       0.543
Bcop_0817
NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR022310:IPR003694; KEGG: bth:BT_0205 NAD synthetase; PFAM: NAD/GMP synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: NAD(+) synthase (glutamine-hydrolyzing); SPTR: Putative uncharacterized protein; TIGRFAM: NAD synthase; IMG reference gene:2504106506; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase.
   
 
 0.508
Bcop_0744
Beta-lactamase domain protein; COGs: COG0426 flavoprotein; InterPro IPR001279:IPR008254; KEGG: bfs:BF0904 putative flavoprotein; PFAM: Beta-lactamase-like; Flavodoxin/nitric oxide synthase; SMART: Beta-lactamase-like; SPTR: Flavoprotein; IMG reference gene:2504106432; PFAM: Metallo-beta-lactamase superfamily; Flavodoxin.
       0.494
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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