STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (508 aa)    
Predicted Functional Partners:
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 0.999
Bcop_2234
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 0.997
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: bfs:BF3604 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Putative glucose-6-phosphate isomerase; IMG reference gene:2504108184; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 
 0.958
Bcop_0944
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: bvu:BVU_3585 glyceraldehyde 3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:250 [...]
  
 0.943
Bcop_0428
COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015795:IPR001697; KEGG: bfs:BF4277 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504106091; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.918
Bcop_0929
Fructose-1,6-bisphosphate aldolase, class II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: bfs:BF3138 fructose-bisphosphate aldolase; PFAM: Ketose-bisphosphate aldolase, class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-bisphosphate aldolase; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class 2; Ketose-bisphosphate aldolase, class-II; IMG reference gene:2504106625; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochon [...]
   
 
 0.906
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 
 0.905
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.903
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.901
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 
 0.900
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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