node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAI64442.1 | BAI65015.1 | RMDY18_06100 | RMDY18_11830 | Sec-independent protein secretion pathway component. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.655 |
BAI64442.1 | ftsY | RMDY18_06100 | RMDY18_11600 | Sec-independent protein secretion pathway component. | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.703 |
BAI64442.1 | secA | RMDY18_06100 | RMDY18_06720 | Sec-independent protein secretion pathway component. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.698 |
BAI64442.1 | secD | RMDY18_06100 | RMDY18_09520 | Sec-independent protein secretion pathway component. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.650 |
BAI64442.1 | secE | RMDY18_06100 | RMDY18_04260 | Sec-independent protein secretion pathway component. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.476 |
BAI64442.1 | tatA | RMDY18_06100 | RMDY18_10420 | Sec-independent protein secretion pathway component. | Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.833 |
BAI64442.1 | tatC | RMDY18_06100 | RMDY18_10430 | Sec-independent protein secretion pathway component. | Sec-independent protein secretion pathway component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.953 |
BAI64876.1 | tatA | RMDY18_10440 | RMDY18_10420 | Superfamily II RNA helicase. | Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.468 |
BAI64876.1 | tatC | RMDY18_10440 | RMDY18_10430 | Superfamily II RNA helicase. | Sec-independent protein secretion pathway component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.577 |
BAI65015.1 | BAI64442.1 | RMDY18_11830 | RMDY18_06100 | Signal peptidase I; Belongs to the peptidase S26 family. | Sec-independent protein secretion pathway component. | 0.655 |
BAI65015.1 | ftsY | RMDY18_11830 | RMDY18_11600 | Signal peptidase I; Belongs to the peptidase S26 family. | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.708 |
BAI65015.1 | secA | RMDY18_11830 | RMDY18_06720 | Signal peptidase I; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.744 |
BAI65015.1 | secD | RMDY18_11830 | RMDY18_09520 | Signal peptidase I; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.682 |
BAI65015.1 | secE | RMDY18_11830 | RMDY18_04260 | Signal peptidase I; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.658 |
BAI65015.1 | secY | RMDY18_11830 | RMDY18_05000 | Signal peptidase I; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.592 |
BAI65015.1 | tatC | RMDY18_11830 | RMDY18_10430 | Signal peptidase I; Belongs to the peptidase S26 family. | Sec-independent protein secretion pathway component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.559 |
BAI65734.1 | tatC | RMDY18_19020 | RMDY18_10430 | Putative multicopper oxidase. | Sec-independent protein secretion pathway component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.630 |
ftsY | BAI64442.1 | RMDY18_11600 | RMDY18_06100 | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Sec-independent protein secretion pathway component. | 0.703 |
ftsY | BAI65015.1 | RMDY18_11600 | RMDY18_11830 | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Signal peptidase I; Belongs to the peptidase S26 family. | 0.708 |
ftsY | secA | RMDY18_11600 | RMDY18_06720 | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.968 |