STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhMalate/lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (319 aa)    
Predicted Functional Partners:
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.953
BAI64257.1
Aspartate/tyrosine/aromatic aminotransferase.
  
 0.933
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.923
mqo
Predicted dehydrogenase.
    
 0.919
BAI63918.1
NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.851
BAI64044.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.830
BAI64947.1
Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.812
BAI63886.1
NAD-specific glutamate dehydrogenase.
     
  0.800
BAI64543.1
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component; Related enzyme.
  
 
 0.773
BAI64668.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.740
Your Current Organism:
Rothia mucilaginosa
NCBI taxonomy Id: 680646
Other names: R. mucilaginosa DY-18, Rothia mucilaginosa DY-18, Rothia mucilaginosa str. DY-18, Rothia mucilaginosa strain DY-18
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