STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (958 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.924
AEU35389.1
TIGRFAM: Pyruvate kinase; KEGG: aca:ACP_1882 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family.
     
 0.922
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 
 0.922
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.921
AEU37063.1
TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: aca:ACP_1789 citrate synthase 2; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
  
  
 0.845
AEU35217.1
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
    
 0.828
AEU36496.1
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
    
 0.828
AEU35243.1
PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sus:Acid_0182 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
   
 
 0.821
AEU36854.1
Formate dehydrogenase, alpha subunit; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; TIGRFAM: Formate dehydrogenase, alpha subunit; KEGG: aca:ACP_0320 formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Molybdopterin oxidoreductase, Fe4S4 domain.
     
 0.803
AEU34372.1
SMART: Cupin 1; TIGRFAM: Bicupin, oxalate decarboxylase/oxidase; Twin-arginine translocation pathway, signal sequence; KEGG: sno:Snov_1310 bicupin, oxalate decarboxylase family; PFAM: Cupin 1.
     
  0.800
Your Current Organism:
Granulicella mallensis
NCBI taxonomy Id: 682795
Other names: G. mallensis MP5ACTX8, Granulicella mallensis MP5ACTX8, Granulicella mallensis str. MP5ACTX8, Granulicella mallensis strain MP5ACTX8, Granulicella sp. MP5ACTX8
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