STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCAL_078343-hydroxy-3-methylglutaryl coenzyme A reductase. (930 aa)    
Predicted Functional Partners:
TCAL_09243
HMG_CoA_synt_C domain-containing protein.
  
 
 0.999
TCAL_13241
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 
 0.935
TCAL_03090
Mevalonate kinase.
  
 0.923
TCAL_00728
Mevalonate kinase.
  
 0.923
TCAL_11736
Uncharacterized protein.
    
 0.847
TCAL_07332
Pyruvate carboxyltransferase domain-containing protein.
    
 0.837
TCAL_00255
Uncharacterized protein.
  
  
 0.821
TCAL_05048
FAD_binding_3 domain-containing protein.
   
  
 0.806
TCAL_16724
FAD_binding_3 domain-containing protein.
   
  
 0.806
TCAL_03351
BHLH domain-containing protein.
     
 0.769
Your Current Organism:
Tigriopus californicus
NCBI taxonomy Id: 6832
Other names: T. californicus, tidepool copepod
Server load: low (28%) [HD]