STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL52185.1DNA ligase D. (329 aa)    
Predicted Functional Partners:
SCL47516.1
Bifunctional non-homologous end joining protein LigD; Manually curated.
  
 0.992
SCL52213.1
ATP-dependent DNA ligase.
  
 0.968
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.915
SCL61613.1
DNA ligase-1.
 
  
 0.832
SCL47518.1
Bifunctional non-homologous end joining protein LigD.
 
  
 
0.760
SCL52182.1
Peptide-methionine (R)-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family.
       0.600
SCL51813.1
ATP dependent helicase, Lhr family.
  
     0.459
SCL53455.1
DNA topoisomerase IB; Manually curated.
 
    0.434
SCL66026.1
formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.
  
     0.415
SCL65290.1
Putative hydrolase.
 
   
 0.402
Your Current Organism:
Micromonospora yangpuensis
NCBI taxonomy Id: 683228
Other names: CGMCC 4.5736, DSM 45577, M. yangpuensis, Micromonospora sp. FXJ6.011, Micromonospora yangpuensis Zhang et al. 2012, NBRC 107727, strain FXJ6.011
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