node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIC28968.1 | EIC28970.1 | Metal_1157 | Metal_1159 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.839 |
EIC28968.1 | EIC28972.1 | Metal_1157 | Metal_1161 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit. | 0.476 |
EIC28968.1 | EIC28975.1 | Metal_1157 | Metal_1164 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.870 |
EIC28968.1 | EIC28976.1 | Metal_1157 | Metal_1165 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF. | 0.961 |
EIC28968.1 | EIC28977.1 | Metal_1157 | Metal_1166 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.967 |
EIC28968.1 | EIC28978.1 | Metal_1157 | Metal_1167 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE; manually curated. | 0.870 |
EIC28968.1 | EIC30687.1 | Metal_1157 | Metal_3007 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase. | 0.803 |
EIC28968.1 | EIC30688.1 | Metal_1157 | Metal_3008 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA). | 0.819 |
EIC28968.1 | hypA | Metal_1157 | Metal_3004 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.948 |
EIC28970.1 | EIC28968.1 | Metal_1159 | Metal_1157 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | 0.839 |
EIC28970.1 | EIC28972.1 | Metal_1159 | Metal_1161 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit. | 0.997 |
EIC28970.1 | EIC28975.1 | Metal_1159 | Metal_1164 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.731 |
EIC28970.1 | EIC28976.1 | Metal_1159 | Metal_1165 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF. | 0.728 |
EIC28970.1 | EIC28977.1 | Metal_1159 | Metal_1166 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.762 |
EIC28970.1 | EIC28978.1 | Metal_1159 | Metal_1167 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE; manually curated. | 0.719 |
EIC28970.1 | EIC30687.1 | Metal_1159 | Metal_3007 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase. | 0.739 |
EIC28970.1 | EIC30688.1 | Metal_1159 | Metal_3008 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA). | 0.674 |
EIC28970.1 | hypA | Metal_1159 | Metal_3004 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.403 |
EIC28972.1 | EIC28968.1 | Metal_1161 | Metal_1157 | Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | 0.476 |
EIC28972.1 | EIC28970.1 | Metal_1161 | Metal_1159 | Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit. | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.997 |