STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3MEE9Autophagy_act_C domain-containing protein. (198 aa)    
Predicted Functional Partners:
A0A5C3LPY0
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
    
 0.929
A0A5C3LQT9
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
    
 0.929
A0A5C3LX33
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 0.919
A0A5C3MI44
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
    
 0.822
A0A5C3MEW2
E2_bind domain-containing protein.
   
 0.775
A0A5C3LN89
Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family.
   
 0.765
A0A5C3LQ22
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.
   
 0.765
A0A5C3M5D1
Rhodanese domain-containing protein.
   
 0.765
A0A5C3MCX7
Ubiquitin activating enzyme.
   
 0.765
A0A5C3MHJ6
ThiF domain-containing protein.
   
 0.765
Your Current Organism:
Crucibulum laeve
NCBI taxonomy Id: 68775
Other names: C. laeve
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.