STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLE_5425Nuclease. (592 aa)    
Predicted Functional Partners:
GLE_0778
Extracellular ribonuclease precursor.
  
 0.931
GLE_4313
Nuclease.
 
     0.742
GLE_4311
Nuclease.
  
     0.729
GLE_1749
Peptidase, families S8 and S53.
  
  
  0.711
GLE_1595
Endonuclease/exonuclease/phosphatase family.
 
     0.682
cysN
Bifunctional enzyme CysN/cysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
    
  0.600
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.594
GLE_2637
Subtilisin N-terminal region/peptidase, families S8 and S53; Belongs to the peptidase S8 family.
  
    0.585
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.582
GLE_5426
Hypothetical protein.
       0.557
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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