STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TK0551D-isomer specific 2-hydroxyacid dehydrogenase. (333 aa)    
Predicted Functional Partners:
TK1966
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
0.926
apgM
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
  0.914
TK0552
Hypothetical protein.
       0.790
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 
 0.736
tdh
Threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate. To a lesser extent, also catalyzes the oxidation of L-serine; Belongs to the zinc-containing alcohol dehydrogenase family.
  
  
 0.736
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.735
TK1687
Cysteine synthase.
     
 0.720
TK1449
Cystathionine gamma-synthase.
  
  
 0.719
serK
Chromosome partitioning protein ParB homolog; Free serine kinase that uses ADP to phosphorylate L-serine to yield O-phospho-L-serine and AMP.
     
 0.640
tiaS
Nucleic acid-binding protein, containing OB-fold domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
    0.608
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
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