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STRINGSTRING
gyaR protein (Thermococcus kodakarensis) - STRING interaction network
"gyaR" - annotation not available in Thermococcus kodakarensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gyaRannotation not available (333 aa)    
Predicted Functional Partners:
TK2301
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate (239 aa)
   
 
  0.906
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2’-hydroxyl of the adenosine moiety of NAD to yield NADP (278 aa)
   
   
  0.801
TK1687
annotation not available (273 aa)
   
   
  0.747
TK1449
annotation not available (366 aa)
 
     
  0.734
TK0684
annotation not available (364 aa)
         
  0.712
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (431 aa)
   
   
  0.707
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate. To a lesser extent, also catalyzes the oxidation of L-serine; Belongs to the zinc-containing alcohol dehydrogenase family (350 aa)
   
 
  0.700
mutS2
DNA-binding protein MutS2; Has ATPase and non-specific DNA-binding activities (576 aa)
   
        0.637
TK0378
annotation not available (242 aa)
         
  0.608
TK2029
ADP-dependent ribose-1-phosphate kinase; Involved in nucleoside degradation. Phosphorylates ribose 1-phosphate (R1P) to ribose 1,5-bisphosphate. Can also act on deoxyribose 1-phosphate (dR1P), but is most active with R1P. ADP is the most preferred phosphate donor, followed by GDP and UDP; Belongs to the carbohydrate kinase PfkB family (294 aa)
 
   
  0.581
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
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