STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TK0977Pullulanase type II, GH13 family. (765 aa)    
Predicted Functional Partners:
TK1884
Alpha-amylase precursor, GH13 family.
  
  
 0.978
TK1406
Maltodextrin phosphorylase.
 
 0.959
TK1770
Cyclomaltodextrinase.
  
  
0.938
TK1436
Probable alpha-amylase, GH57 family; Catalyzes the formation of branch points in alpha-glucans by cleavage of an alpha-1,4 glycosidic bond and subsequent transfer of the cleaved-off oligosaccharide to a new alpha-1,6 position. The branch chain-length distribution of the reaction products shows degree of polymerization (DP) of 5 to 30, with two local maxima at DP 6 and DP 11. Exhibits an alpha-retaining catalytic mechanism. Does not display alpha-galactosidase or pullulanase activity, since melibiose and pullulan are not substrates. Is not able to catalyze the hydrolysis or transglycosy [...]
  
  
 0.928
TK1809
4-alpha-Glucanotransferase, GH57 family.
    
 0.909
TK0684
Aromatic amino acid permease.
  
 0.871
TK1774
Amylopullulanase, GH57 family.
 
   
 0.809
glmD
Archaeal glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. Involved in chitin degradation.
  
  
 0.779
glmA
exo-beta-D-glucosaminidase; Exo-type enzyme that specifically cleaves the non-reducing terminal glycosidic bond of chitooligosaccharides. Catalyzes the hydrolysis of GlcN- GlcNAc to glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). Involved in chitin degradation. Can also hydrolyze reduced chitobiose (GlcN2OH) and chitooligosaccharides of various chain lengths.
 
  
 0.778
TK1771
ABC-type maltodextrin transport system, maltodextrin-binding periplasmic component.
 
  
 0.777
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
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