STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TK1108Phosphohexomutase; Catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate, and the interconversion of mannose 1-phosphate and mannose 6-phosphate. Also displays low activity with deoxyribose 1- phosphate and glucosamine 1-phosphate; Belongs to the phosphohexose mutase family. (456 aa)    
Predicted Functional Partners:
TK0955
Sugar-phosphate nucleotidyltransferase.
 
 0.993
TK1188
Sugar-phosphate nucleotydyltransferase.
 
 0.993
TK1711
Sugar-phosphate nucleotydyltransferase.
 
 0.989
TK1109
Bifunctional mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 0.982
glkA
ADP-dependent glucokinase; Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate. Involved in chitin degradation.
    
 0.964
fbp
Thermophile-specific fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). Does not display hydrolase activity against fructose 2,6-bisphosphate, fructose 6-phosphate, fructose 1- phosphate, glucose 6-phosphate, and glucose 1-phosphate. Exhibits only negligible activity on inositol-1- phosphate (IMP). Is essential for the growth of T.kodakaraensis under gluconeogen [...]
    
 0.954
TK0219
Sugar-phosphate nucleotidyltransferase.
  
 0.945
pgiA
Archaeal glucose-6-phosphate isomerase; Belongs to the archaeal-type GPI family.
    
  0.945
TK1406
Maltodextrin phosphorylase.
 
 
 0.943
prs
Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). It can also use CTP and GTP as substrates in addition to ATP.
 
 0.938
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
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