node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TK0507 | TK0557 | TK0507 | TK0557 | Adenylate cyclase, class 2. | Predicted ATPase, DUF265 family; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.900 |
TK0507 | TK1179 | TK0507 | TK1179 | Adenylate cyclase, class 2. | Adenylate cyclase, class 2. | 0.918 |
TK0507 | TK2298 | TK0507 | TK2298 | Adenylate cyclase, class 2. | Anaerobic ribonucleoside-triphosphate reductase. | 0.900 |
TK0507 | moaA | TK0507 | TK2225 | Adenylate cyclase, class 2. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.808 |
TK0507 | mptA | TK0507 | TK0793 | Adenylate cyclase, class 2. | Hypothetical protein, conserved, DUF198 family; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.800 |
TK0507 | ndk | TK0507 | TK1307 | Adenylate cyclase, class 2. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.902 |
TK0507 | pyk | TK0507 | TK0511 | Adenylate cyclase, class 2. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.900 |
TK0507 | ribA | TK0507 | TK0428 | Adenylate cyclase, class 2. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.800 |
TK0557 | TK0507 | TK0557 | TK0507 | Predicted ATPase, DUF265 family; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Adenylate cyclase, class 2. | 0.900 |
TK0557 | TK1179 | TK0557 | TK1179 | Predicted ATPase, DUF265 family; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Adenylate cyclase, class 2. | 0.900 |
TK0557 | TK2298 | TK0557 | TK2298 | Predicted ATPase, DUF265 family; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Anaerobic ribonucleoside-triphosphate reductase. | 0.907 |
TK0557 | amzA | TK0557 | TK1178 | Predicted ATPase, DUF265 family; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Hypothetical protein, conserved; Probable zinc metalloprotease whose natural substrate is unknown. | 0.419 |
TK0557 | ndk | TK0557 | TK1307 | Predicted ATPase, DUF265 family; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.953 |
TK0557 | pyk | TK0557 | TK0511 | Predicted ATPase, DUF265 family; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.900 |
TK1179 | TK0507 | TK1179 | TK0507 | Adenylate cyclase, class 2. | Adenylate cyclase, class 2. | 0.918 |
TK1179 | TK0557 | TK1179 | TK0557 | Adenylate cyclase, class 2. | Predicted ATPase, DUF265 family; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.900 |
TK1179 | TK1180 | TK1179 | TK1180 | Adenylate cyclase, class 2. | Hypothetical protein, conserved. | 0.801 |
TK1179 | TK2298 | TK1179 | TK2298 | Adenylate cyclase, class 2. | Anaerobic ribonucleoside-triphosphate reductase. | 0.900 |
TK1179 | amzA | TK1179 | TK1178 | Adenylate cyclase, class 2. | Hypothetical protein, conserved; Probable zinc metalloprotease whose natural substrate is unknown. | 0.801 |
TK1179 | moaA | TK1179 | TK2225 | Adenylate cyclase, class 2. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.808 |