node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TK1482 | mtaD | TK1482 | TK1891 | Purine-nucleoside phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.944 |
TK1482 | mtnP | TK1482 | TK1895 | Purine-nucleoside phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Purine-nucleoside phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.904 |
TK1482 | speE | TK1482 | TK0147 | Purine-nucleoside phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to agmatine to yield N1- aminopropylagmatine. It can also use cadaverine (1,5-diaminopentane) and putrescine (1,4-diaminobutane) as substrate with a lower activity than that of agmatine. The [...] | 0.924 |
TK1888 | TK1889 | TK1888 | TK1889 | Hypothetical membrane protein, conserved. | Hypothetical membrane protein. | 0.671 |
TK1888 | TK1890 | TK1888 | TK1890 | Hypothetical membrane protein, conserved. | Histone macroH2A-related protein (C-terminus). | 0.552 |
TK1888 | mtaD | TK1888 | TK1891 | Hypothetical membrane protein, conserved. | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.458 |
TK1889 | TK1888 | TK1889 | TK1888 | Hypothetical membrane protein. | Hypothetical membrane protein, conserved. | 0.671 |
TK1889 | TK1890 | TK1889 | TK1890 | Hypothetical membrane protein. | Histone macroH2A-related protein (C-terminus). | 0.636 |
TK1889 | mtaD | TK1889 | TK1891 | Hypothetical membrane protein. | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.529 |
TK1890 | TK1888 | TK1890 | TK1888 | Histone macroH2A-related protein (C-terminus). | Hypothetical membrane protein, conserved. | 0.552 |
TK1890 | TK1889 | TK1890 | TK1889 | Histone macroH2A-related protein (C-terminus). | Hypothetical membrane protein. | 0.636 |
TK1890 | TK1892 | TK1890 | TK1892 | Histone macroH2A-related protein (C-terminus). | Hypothetical protein, conserved, DUF553 family fused to N-terminal membrane-bound domain. | 0.412 |
TK1890 | mtaD | TK1890 | TK1891 | Histone macroH2A-related protein (C-terminus). | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.731 |
TK1892 | TK1890 | TK1892 | TK1890 | Hypothetical protein, conserved, DUF553 family fused to N-terminal membrane-bound domain. | Histone macroH2A-related protein (C-terminus). | 0.412 |
TK1892 | mtaD | TK1892 | TK1891 | Hypothetical protein, conserved, DUF553 family fused to N-terminal membrane-bound domain. | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.492 |
mtaD | TK1482 | TK1891 | TK1482 | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Purine-nucleoside phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | 0.944 |
mtaD | TK1888 | TK1891 | TK1888 | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Hypothetical membrane protein, conserved. | 0.458 |
mtaD | TK1889 | TK1891 | TK1889 | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Hypothetical membrane protein. | 0.529 |
mtaD | TK1890 | TK1891 | TK1890 | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Histone macroH2A-related protein (C-terminus). | 0.731 |
mtaD | TK1892 | TK1891 | TK1892 | Probable guanine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Hypothetical protein, conserved, DUF553 family fused to N-terminal membrane-bound domain. | 0.492 |