node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TK0345 | ogt | TK0345 | TK1971 | 3-methyladenine DNA glycosylase. | methylated-DNA-protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | 0.775 |
TK1966 | TK1967 | TK1966 | TK1967 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Distant homolog of phosphate transport system regulator PhoU. | 0.801 |
TK1966 | TK1968 | TK1966 | TK1968 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. | 0.816 |
TK1966 | TK1969 | TK1966 | TK1969 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Hypothetical membrane protein. | 0.801 |
TK1966 | TK1970 | TK1966 | TK1970 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Probable tRNA/rRNA methyltransferase, SpoU family. | 0.687 |
TK1966 | TK1972 | TK1966 | TK1972 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Hypothetical membrane protein, conserved, containing TPR-repeat domains. | 0.714 |
TK1966 | ogt | TK1966 | TK1971 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | methylated-DNA-protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | 0.687 |
TK1966 | truA | TK1966 | TK0927 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.489 |
TK1967 | TK1966 | TK1967 | TK1966 | Distant homolog of phosphate transport system regulator PhoU. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.801 |
TK1967 | TK1968 | TK1967 | TK1968 | Distant homolog of phosphate transport system regulator PhoU. | 2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. | 0.801 |
TK1967 | TK1969 | TK1967 | TK1969 | Distant homolog of phosphate transport system regulator PhoU. | Hypothetical membrane protein. | 0.801 |
TK1967 | TK1970 | TK1967 | TK1970 | Distant homolog of phosphate transport system regulator PhoU. | Probable tRNA/rRNA methyltransferase, SpoU family. | 0.687 |
TK1967 | TK1972 | TK1967 | TK1972 | Distant homolog of phosphate transport system regulator PhoU. | Hypothetical membrane protein, conserved, containing TPR-repeat domains. | 0.695 |
TK1967 | ogt | TK1967 | TK1971 | Distant homolog of phosphate transport system regulator PhoU. | methylated-DNA-protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | 0.687 |
TK1968 | TK1966 | TK1968 | TK1966 | 2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.816 |
TK1968 | TK1967 | TK1968 | TK1967 | 2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. | Distant homolog of phosphate transport system regulator PhoU. | 0.801 |
TK1968 | TK1969 | TK1968 | TK1969 | 2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. | Hypothetical membrane protein. | 0.801 |
TK1968 | TK1970 | TK1968 | TK1970 | 2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. | Probable tRNA/rRNA methyltransferase, SpoU family. | 0.687 |
TK1968 | TK1972 | TK1968 | TK1972 | 2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. | Hypothetical membrane protein, conserved, containing TPR-repeat domains. | 0.687 |
TK1968 | ogt | TK1968 | TK1971 | 2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. | methylated-DNA-protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | 0.687 |