STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tk-hypCHydrogenase expression/formation protein HypC. (75 aa)    
Predicted Functional Partners:
Tk-hypD
Hydrogenase expression/formation protein hypD.
 
 
 0.999
TK1993
Hydrogenase expression/formation protein HypE.
 
 
 0.998
hypA
Hydrogenase nickel-incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Belongs to the HypA/HybF family.
 
  
 0.942
TK1997
Hydrogenase maturation protein HypF.
 
 
 0.941
hydA
Cytosolic NiFe-hydrogenase, alpha subunit.
 
 
 0.836
TK0961
Hydrogenase expression/formation protein HypE.
 
 
 0.660
TK1032
Hydrogenase expression/formation protein HypE.
 
 
 0.628
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
       0.600
TK0524
Rubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
  
  
 0.560
TK2091
Membrane bound hydrogenase, NiFe-hydrogenase large subunit 2.
   
 
 0.537
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
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