node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TK0684 | cpkA | TK0684 | TK2158 | Aromatic amino acid permease. | Carbamate kinase-like carbamoyl phosphate synthetase. | 0.740 |
TK0684 | glnA | TK0684 | TK1796 | Aromatic amino acid permease. | Glutamine synthetase; Carries out the ATP-dependent synthesis of glutamine from ammonium nitrogen and glutamate. Exhibits both L-gamma- glutamylhydroxamate synthetase and gamma-glutamyltransferase activities when using hydroxylamine as substrate; in fact, the enzyme possesses low biosynthetic activity, suggesting that the reaction is biased towards the degradation of glutamine under ammonia-rich conditions. Might play some role in ammonia assimilation under ammonia-starvation conditions. Can also use GTP instead of ATP in the synthetase reaction, but not CTP or UTP. | 0.511 |
TK2156 | TK2159 | TK2156 | TK2159 | RNA-binding protein, containing PUA domain. | Predicted oxidoreductase. | 0.476 |
TK2156 | cpkA | TK2156 | TK2158 | RNA-binding protein, containing PUA domain. | Carbamate kinase-like carbamoyl phosphate synthetase. | 0.495 |
TK2159 | TK2156 | TK2159 | TK2156 | Predicted oxidoreductase. | RNA-binding protein, containing PUA domain. | 0.476 |
TK2159 | cpkA | TK2159 | TK2158 | Predicted oxidoreductase. | Carbamate kinase-like carbamoyl phosphate synthetase. | 0.651 |
argF | cpkA | TK0871 | TK2158 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Carbamate kinase-like carbamoyl phosphate synthetase. | 0.935 |
argF | gdhA | TK0871 | TK1431 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Glutamate dehydrogenase. | 0.466 |
argF | pyrB | TK0871 | TK2196 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Aspartate carbamoyltransferase, catalytic subunit. | 0.823 |
argF | pyrI | TK0871 | TK2195 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.808 |
argF | tpiA | TK0871 | TK2129 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.554 |
cpkA | TK0684 | TK2158 | TK0684 | Carbamate kinase-like carbamoyl phosphate synthetase. | Aromatic amino acid permease. | 0.740 |
cpkA | TK2156 | TK2158 | TK2156 | Carbamate kinase-like carbamoyl phosphate synthetase. | RNA-binding protein, containing PUA domain. | 0.495 |
cpkA | TK2159 | TK2158 | TK2159 | Carbamate kinase-like carbamoyl phosphate synthetase. | Predicted oxidoreductase. | 0.651 |
cpkA | argF | TK2158 | TK0871 | Carbamate kinase-like carbamoyl phosphate synthetase. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.935 |
cpkA | gdhA | TK2158 | TK1431 | Carbamate kinase-like carbamoyl phosphate synthetase. | Glutamate dehydrogenase. | 0.914 |
cpkA | glnA | TK2158 | TK1796 | Carbamate kinase-like carbamoyl phosphate synthetase. | Glutamine synthetase; Carries out the ATP-dependent synthesis of glutamine from ammonium nitrogen and glutamate. Exhibits both L-gamma- glutamylhydroxamate synthetase and gamma-glutamyltransferase activities when using hydroxylamine as substrate; in fact, the enzyme possesses low biosynthetic activity, suggesting that the reaction is biased towards the degradation of glutamine under ammonia-rich conditions. Might play some role in ammonia assimilation under ammonia-starvation conditions. Can also use GTP instead of ATP in the synthetase reaction, but not CTP or UTP. | 0.920 |
cpkA | purQ | TK2158 | TK0201 | Carbamate kinase-like carbamoyl phosphate synthetase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.902 |
cpkA | pyrB | TK2158 | TK2196 | Carbamate kinase-like carbamoyl phosphate synthetase. | Aspartate carbamoyltransferase, catalytic subunit. | 0.896 |
cpkA | pyrI | TK2158 | TK2195 | Carbamate kinase-like carbamoyl phosphate synthetase. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.811 |