STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)    
Predicted Functional Partners:
G3P458_GASAC
Platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit.
    
 0.964
G3QAJ4_GASAC
Platelet-activating factor acetylhydrolase 1b, catalytic subunit 2.
    
 0.964
G3NXV2_GASAC
NudC nuclear distribution protein.
   
 0.933
G3NTF7_GASAC
Dynactin 2 (p50).
    
 0.910
DYNC1I1
Dynein cytoplasmic 1 intermediate chain 1.
   
 0.883
G3NMN6_GASAC
Dynein, cytoplasmic 1, intermediate chain 2a.
   
 0.880
G3PRX3_GASAC
Dynein cytoplasmic 1 intermediate chain 2.
   
 0.880
G3NMJ3_GASAC
Dynactin 1b.
    
 0.877
G3Q8T6_GASAC
CAP-Gly domain-containing protein.
    
 0.877
G3NM90_GASAC
Platelet-activating factor acetylhydrolase.
     
 0.875
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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