STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3PRJ8_GASACEarly growth response 2b. (442 aa)    
Predicted Functional Partners:
G3P9P4_GASAC
Early growth response 3.
  
0.917
G3Q265_GASAC
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
  
0.914
G3N5K2_GASAC
NGFI-A binding protein 2 (EGR1 binding protein 2).
   
 0.902
G3PBM0_GASAC
CREB binding protein b.
    
 0.881
G3Q4J0_GASAC
CREB binding protein a.
    
 0.881
G3NM42_GASAC
E1A binding protein p300 a.
    
  0.879
G3NY16_GASAC
E1A binding protein p300 b.
    
  0.879
G3P5Q9_GASAC
FBJ murine osteosarcoma viral oncogene homolog B.
   
 0.872
EGR2
Early growth response 2.
  
 
 
0.857
G3PC67_GASAC
Uncharacterized protein.
    
  0.848
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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