STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (403 aa)    
Predicted Functional Partners:
CBR_g26360
3'-5' exonuclease domain-containing protein.
  
 0.998
CBR_g39230
Uncharacterized protein.
  
 0.998
CBR_g8027
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.993
CBR_g29902
DNA ligase.
  
 0.990
CBR_g38906
DNA polymerase.
   
 0.984
CBR_g45434
DNA ligase.
  
 0.970
CBR_g48040
Mre11_DNA_bind domain-containing protein.
   
 0.965
CBR_g29296
AAA domain-containing protein.
   
 0.920
CBR_g30807
Reverse transcriptase domain-containing protein.
   
 0.919
CBR_g44539
AAA_23 domain-containing protein.
  
 0.907
Your Current Organism:
Chara braunii
NCBI taxonomy Id: 69332
Other names: C. braunii
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