node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEA46045.1 | AEA47537.1 | Arcve_0001 | Arcve_1535 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | 0.993 |
AEA46045.1 | fen | Arcve_0001 | Arcve_2015 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.855 |
AEA46045.1 | pcn | Arcve_0001 | Arcve_1387 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.976 |
AEA46045.1 | polB | Arcve_0001 | Arcve_1710 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.812 |
AEA46045.1 | polC | Arcve_0001 | Arcve_1012 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | Transcriptional regulator, XRE family; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. | 0.610 |
AEA46045.1 | priL | Arcve_0001 | Arcve_1388 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.992 |
AEA46045.1 | rfcL | Arcve_0001 | Arcve_0620 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.952 |
AEA46045.1 | rfcS | Arcve_0001 | Arcve_1881 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.956 |
AEA46045.1 | rnhB | Arcve_0001 | Arcve_1232 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.848 |
AEA46045.1 | rpl40e | Arcve_0001 | Arcve_1459 | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | HAMAP: 50S ribosomal protein L40e; KEGG: fpl:Ferp_1991 50S ribosomal protein L40e; SPTR: 50S ribosomal protein L40e; PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.812 |
AEA47537.1 | AEA46045.1 | Arcve_1535 | Arcve_0001 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | 0.993 |
AEA47537.1 | fen | Arcve_1535 | Arcve_2015 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.994 |
AEA47537.1 | pcn | Arcve_1535 | Arcve_1387 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.999 |
AEA47537.1 | polB | Arcve_1535 | Arcve_1710 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.998 |
AEA47537.1 | priL | Arcve_1535 | Arcve_1388 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.998 |
AEA47537.1 | rfcL | Arcve_1535 | Arcve_0620 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.936 |
AEA47537.1 | rfcS | Arcve_1535 | Arcve_1881 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.929 |
AEA47537.1 | rnhB | Arcve_1535 | Arcve_1232 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.874 |
AEA47537.1 | rpl40e | Arcve_1535 | Arcve_1459 | COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006133: IPR006134: IPR004578: IPR006172; KEGG: fpl:Ferp_1482 DNA polymerase Pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | HAMAP: 50S ribosomal protein L40e; KEGG: fpl:Ferp_1991 50S ribosomal protein L40e; SPTR: 50S ribosomal protein L40e; PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.927 |
fen | AEA46045.1 | Arcve_2015 | Arcve_0001 | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | Transcriptional regulator, XRE family; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterProIPR001208: IPR001387: IPR003587: IPR003586: IPR 006141; KEGG: fpl:Ferp_0980 transcriptional regulator, XRE family; PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: Hedgehog/intein hint, N-terminal; DNA-dependent ATPase MCM; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; SPTR: Transcriptional regulator, XRE family; manually curated; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal spl [...] | 0.855 |