node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADQ78643.1 | ADQ78644.1 | Palpr_0484 | Palpr_0485 | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfs:BF2260 putative flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | 0.578 |
ADQ78643.1 | glyA | Palpr_0484 | Palpr_0486 | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfs:BF2260 putative flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.469 |
ADQ78643.1 | pyrB | Palpr_0484 | Palpr_0482 | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfs:BF2260 putative flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: bfs:BF2262 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: a [...] | 0.641 |
ADQ78643.1 | pyrI | Palpr_0484 | Palpr_0483 | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfs:BF2260 putative flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.759 |
ADQ78644.1 | ADQ78643.1 | Palpr_0485 | Palpr_0484 | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfs:BF2260 putative flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. | 0.578 |
ADQ78644.1 | ADQ78646.1 | Palpr_0485 | Palpr_0487 | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | Hypothetical protein; InterPro IPR012657; KEGG: dfe:Dfer_5056 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: S23 ribosomal protein; TIGRFAM: conserved hypothetical protein TIGR02436. | 0.425 |
ADQ78644.1 | glyA | Palpr_0485 | Palpr_0486 | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.550 |
ADQ78644.1 | pyrB | Palpr_0485 | Palpr_0482 | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: bfs:BF2262 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: a [...] | 0.458 |
ADQ78644.1 | pyrI | Palpr_0485 | Palpr_0483 | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.549 |
ADQ78646.1 | ADQ78644.1 | Palpr_0487 | Palpr_0485 | Hypothetical protein; InterPro IPR012657; KEGG: dfe:Dfer_5056 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: S23 ribosomal protein; TIGRFAM: conserved hypothetical protein TIGR02436. | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | 0.425 |
ADQ78646.1 | glyA | Palpr_0487 | Palpr_0486 | Hypothetical protein; InterPro IPR012657; KEGG: dfe:Dfer_5056 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: S23 ribosomal protein; TIGRFAM: conserved hypothetical protein TIGR02436. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.596 |
glyA | ADQ78643.1 | Palpr_0486 | Palpr_0484 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfs:BF2260 putative flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. | 0.469 |
glyA | ADQ78644.1 | Palpr_0486 | Palpr_0485 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | 0.550 |
glyA | ADQ78646.1 | Palpr_0486 | Palpr_0487 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein; InterPro IPR012657; KEGG: dfe:Dfer_5056 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: S23 ribosomal protein; TIGRFAM: conserved hypothetical protein TIGR02436. | 0.596 |
glyA | pyrB | Palpr_0486 | Palpr_0482 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: bfs:BF2262 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: a [...] | 0.534 |
glyA | pyrI | Palpr_0486 | Palpr_0483 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.464 |
pyrB | ADQ78643.1 | Palpr_0482 | Palpr_0484 | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: bfs:BF2262 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: a [...] | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfs:BF2260 putative flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. | 0.641 |
pyrB | ADQ78644.1 | Palpr_0482 | Palpr_0485 | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: bfs:BF2262 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: a [...] | COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: fjo:Fjoh_0863 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Chloramphenicol acetyltransferase (CAT-III); PFAM: Chloramphenicol acetyltransferase. | 0.458 |
pyrB | glyA | Palpr_0482 | Palpr_0486 | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: bfs:BF2262 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: a [...] | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.534 |
pyrB | pyrI | Palpr_0482 | Palpr_0483 | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: bfs:BF2262 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: a [...] | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.999 |