STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ78836.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: chu:CHU_0250 NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. (431 aa)    
Predicted Functional Partners:
ADQ79253.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: aps:CFPG_312 glutamate synthase large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
   
  
 0.534
ADQ81179.1
COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: pdi:BDI_2081 peptidyl-prolyl cis-trans isomerase SlyD, FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
  
    0.514
ADQ78521.1
COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterProIPR003916: IPR018393: IPR001516: IPR001750: IPR 003945; KEGG: bth:BT_4060 NADH dehydrogenase I, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: Proton-translocating NADH-quinone oxidoreductase, L subunit; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 [...]
  
  
 0.509
ADQ79150.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872: IPR015590: IPR016160; KEGG: bvu:BVU_3604 putative proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydraogenase; PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; SPTR: Putative uncharacterized protein; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
 
  
 0.506
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.469
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.453
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
   
 
 0.444
ADQ79193.1
COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804: IPR019818: IPR004790; KEGG: fps:FP1872 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase (NADP+); TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, eukaryotic type; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
  
 0.436
ADQ81064.1
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
  
 0.434
ADQ78531.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900: IPR011894; KEGG: bfs:BF3168 putative pyruvate-flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate:ferredoxin (Flavodoxin) oxidoreductase; TIGRFAM: pyruvate ferredoxin/ [...]
  
  
 0.424
Your Current Organism:
Paludibacter propionicigenes
NCBI taxonomy Id: 694427
Other names: P. propionicigenes WB4, Paludibacter propionicigenes CCUG 53888, Paludibacter propionicigenes DSM 17365, Paludibacter propionicigenes JCM 13257, Paludibacter propionicigenes WB4, Paludibacter propionicigenes str. WB4, Paludibacter propionicigenes strain WB4
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