STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (170 aa)    
Predicted Functional Partners:
ADQ79662.1
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
 0.992
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.986
ADQ80930.1
COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR013708: IPR006151; KEGG: bvu:BVU_2541 shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain; TIGRFAM: shikimate 5-dehydrogenase.
 
 
 0.979
ADQ79669.1
Chorismate mutase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002701: IPR006218: IPR020822; KEGG: bth:BT_3934 putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase.
 
  
 0.837
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.800
ADQ79983.1
Hypothetical protein.
       0.569
ADQ81021.1
COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR000991: IPR006221: IPR006220: IPR011702: IPR 001317: IPR017926; KEGG: pdi:BDI_0590 anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; SPTR: Anthranilate synthase component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.
 
   
 0.557
ADQ79080.1
KEGG: bvu:BVU_3042 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.555
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
   
 0.542
ADQ79981.1
Beta-ketoacyl-acyl-carrier-protein synthase III; COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR013751: IPR013747; KEGG: rbi:RB2501_06125 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase III; SPTR: 3-oxoacyl-[acyl-carrier protein] synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl [...]
     
 0.495
Your Current Organism:
Paludibacter propionicigenes
NCBI taxonomy Id: 694427
Other names: P. propionicigenes WB4, Paludibacter propionicigenes CCUG 53888, Paludibacter propionicigenes DSM 17365, Paludibacter propionicigenes JCM 13257, Paludibacter propionicigenes WB4, Paludibacter propionicigenes str. WB4, Paludibacter propionicigenes strain WB4
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