STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7P6A6_IXOSCDihydrolipoamide dehydrogenase, putative (Fragment). (346 aa)    
Predicted Functional Partners:
B7Q1W9_IXOSC
Dihydrolipoamide acetyltransferase, putative (Fragment).
 
 0.971
B7PZE3_IXOSC
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.968
B7PR86_IXOSC
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 
 0.934
B7PCU5_IXOSC
2-oxoglutarate dehydrogenase, putative.
  
 0.926
B7PR76_IXOSC
Branched chain alpha-keto acid dehydrogenase, putative (Fragment).
 
 0.910
B7PEH7_IXOSC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.905
B7P8B9_IXOSC
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.871
B7QA77_IXOSC
Dihydrolipoamide acetyltransferase, putative (Fragment).
 0.858
B7PI06_IXOSC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.851
B7QA75_IXOSC
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.817
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.