STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7PFF2_IXOSCProtein smg7, putative. (585 aa)    
Predicted Functional Partners:
B7QF19_IXOSC
Fkbp-rapamycin associated protein, putative; Belongs to the PI3/PI4-kinase family.
   
 0.980
B7PZ74_IXOSC
Nonsense-mediated mRNA decay protein, putative.
   
 0.948
B7P8N1_IXOSC
RNA binding domain-containing protein, putative.
    
 0.945
B7PVX2_IXOSC
Telomerase-binding protein EST1A, putative.
    
0.937
B7PKL9_IXOSC
Uncharacterized protein.
   
 0.924
B7PKM1_IXOSC
Uncharacterized protein.
   
 0.924
B7Q7R2_IXOSC
Regulator of nonsense transcripts 3B, putative.
   
 0.875
B7PZM0_IXOSC
Uncharacterized protein.
   
 
 0.841
B7QCT6_IXOSC
Uncharacterized protein.
     
 0.807
Cbp20
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
   
 0.777
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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