STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7PJJ2_IXOSCFormin homology 2 domaincontaining protein. (763 aa)    
Predicted Functional Partners:
B7QHT2_IXOSC
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
    
 0.846
B7PZM8_IXOSC
Rhogtpase, putative.
    
 0.705
B7PGM8_IXOSC
Sulfite-dehydrogenase, putative (Fragment); Belongs to the cytochrome b5 family.
      
 0.704
B7PHU6_IXOSC
Dishevelled protein, putative (Fragment).
    
 0.605
B7P258_IXOSC
Actin, putative; Belongs to the actin family.
    
 0.554
B7PBG2_IXOSC
Actin, putative; Belongs to the actin family.
    
 0.554
B7PJB0_IXOSC
Anillin/rhotekin, putative.
   
 0.553
B7QHM4_IXOSC
Zinc finger protein, putative.
   
 0.553
B7QDE8_IXOSC
Actin, putative.
    
 0.548
B7QJ40_IXOSC
Proline-rich cell wall protein, putative.
    
 0.541
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.