STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7PJK0_IXOSCATPase family AAA domaincontaining protein 5-like, putative. (894 aa)    
Predicted Functional Partners:
B7PGP8_IXOSC
Replication factor C, subunit RFC3, putative.
   
 0.985
B7QJ79_IXOSC
Replication factor C, subunit RFC2, putative.
   
 0.980
B7Q7U8_IXOSC
Replication factor C, subunit RFC2, putative.
   
 0.979
B7QFN6_IXOSC
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.973
B7QD01_IXOSC
Replication factor C, subunit RFC4, putative.
   
 0.949
B7QHT5_IXOSC
Replication factor C, subunit RFC4, putative.
   
 0.949
B7Q750_IXOSC
Structural maintenance of chromosomes protein.
   
 
 0.940
B7Q1M0_IXOSC
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.936
B7PQL8_IXOSC
WD-repeat protein, putative.
   
 
 0.935
B7QIN2_IXOSC
Cell cycle checkpoint protein rad17, putative.
   
 0.915
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.