STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7PUM9_IXOSCUbiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (702 aa)    
Predicted Functional Partners:
B7PSN5_IXOSC
Autophagy-related protein 3.
    
 0.998
B7PFP1_IXOSC
Gamma-aminobutyric acid receptor associated protein, putative (Fragment).
   
 0.996
B7PJP0_IXOSC
Gamma-aminobutyric acid receptor associated protein, putative.
   
 0.996
B7P118_IXOSC
Microtubule-associated proteins 1A/1B light chain, putative.
   
 0.927
B7PHQ2_IXOSC
WD-repeat protein, putative (Fragment).
    
 0.908
B7QF57_IXOSC
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 0.899
B7P306_IXOSC
WD domain and G-beta repeat containing protein, putative (Fragment).
     
 0.878
Q4PM08_IXOSC
Ribosomal protein L40, putative.
    
 0.812
B7PR84_IXOSC
Ubiquitin-activating enzyme E1, putative; Belongs to the ubiquitin-activating E1 family.
    
 0.779
B7PA91_IXOSC
Ubiquitin protein ligase, putative; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.774
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.