STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7PZC2_IXOSCCpg binding protein, putative (Fragment). (420 aa)    
Predicted Functional Partners:
B7QLL6_IXOSC
Trithorax protein ash2, putative.
   
 0.997
B7PWV2_IXOSC
Retinoblastoma binding protein, putative.
    
 0.996
B7QNH5_IXOSC
DPY-30 protein, putative.
    
 0.979
B7QBD7_IXOSC
WD-repeat protein, putative.
    
 0.978
B7Q092_IXOSC
Mixed-lineage leukemia protein, mll, putative.
   
 0.956
B7Q093_IXOSC
RRM domain-containing protein.
   
 0.956
B7PZR2_IXOSC
THO complex subunit, putative.
   
 0.944
B7PID4_IXOSC
Guanine nucleotide exchange factor (GBF1), putative.
   
 
 0.875
Q4PM69_IXOSC
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.805
B7Q065_IXOSC
Actin, putative; Belongs to the actin family.
    
 
 0.770
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.