STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7QE75_IXOSCDiacylglycerol kinase. (831 aa)    
Predicted Functional Partners:
B7P6Q5_IXOSC
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.953
B7PM35_IXOSC
Phopholipase D, putative (Fragment).
    
 0.932
B7PQS9_IXOSC
Lipin, putative.
     
 0.930
B7Q2N6_IXOSC
Phosphoinositide phospholipase C.
   
 0.929
B7P4F8_IXOSC
Phosphatidate phosphatase, putative.
   
 0.925
B7PMH4_IXOSC
acidPPc domain-containing protein.
   
 0.920
B7P5R7_IXOSC
Diacylglycerol kinase.
     
0.918
B7PG26_IXOSC
Diacylglycerol kinase.
     
0.917
B7QFN8_IXOSC
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
    
 0.917
B7P4X9_IXOSC
Phosphoinositide phospholipase C.
    
 0.911
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.