STRINGSTRING
iscU protein (Midichloria mitochondrii) - STRING interaction network
"iscU" - FeS cluster assembly scaffold IscU in Midichloria mitochondrii
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
iscUFeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (131 aa)    
Predicted Functional Partners:
midi_00283
Cysteine desulfurase 2 (520 aa)
   
  0.999
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins (396 aa)
   
  0.999
fdx
Ferredoxin (110 aa)
   
  0.998
midi_00331
Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (198 aa)
   
 
  0.990
hscA
Chaperone protein, HscA (499 aa)
   
 
  0.964
iscA
Iron sulfur cluster assembly accessory protein (110 aa)
   
   
  0.961
dnaK
Molecular chaperone DnaK; Acts as a chaperone (631 aa)
   
 
  0.885
midi_00253
NifU domain-containing protein (197 aa)
   
 
  0.743
midi_00187
Putative Iron sulfur cluster assembly accessory protein (108 aa)
   
   
  0.679
sodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (207 aa)
   
 
  0.669
Your Current Organism:
Midichloria mitochondrii
NCBI taxonomy Id: 696127
Other names: C. Midichloria, C. Midichloria mitochondrii, C. Midichloria mitochondrii IricVA, Candidatus Midichloria, Candidatus Midichloria mitochondrii, Candidatus Midichloria mitochondrii IricVA, Candidatus Midichloria mitochondrii str. IricVA, Candidatus Midichloria mitochondrii strain IricVA, Ixodes ricinus endosymbiont, Ixodes ricinus endosymbiont 1 (IricES1), Midichloria, Midichloria mitochondrii, Midichloria mitochondrii IricVA, endosymbiont of Ixodes ricinus
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