STRINGSTRING
hemK protein (Midichloria mitochondrii) - STRING interaction network
"hemK" - Modification methylase, HemK family in Midichloria mitochondrii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemKModification methylase, HemK family (262 aa)    
Predicted Functional Partners:
prfA
Protein chain release factor A; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (359 aa)
 
  0.995
midi_00697
Putative yrdC domain-containing protein (196 aa)
 
   
  0.872
midi_00381
Hypothetical protein (182 aa)
 
        0.786
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (223 aa)
 
 
   
  0.785
midi_00467
5-formyltetrahydrofolate cyclo-ligase (202 aa)
         
  0.722
midi_00466
Hypothetical protein (154 aa)
              0.718
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (271 aa)
 
   
  0.612
thyX
FAD-dependent thymidylate synthase; Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (313 aa)
     
      0.573
midi_00176
Surface antigen (608 aa)
     
      0.557
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (185 aa)
 
        0.555
Your Current Organism:
Midichloria mitochondrii
NCBI taxonomy Id: 696127
Other names: C. Midichloria, C. Midichloria mitochondrii, C. Midichloria mitochondrii IricVA, Candidatus Midichloria, Candidatus Midichloria mitochondrii, Candidatus Midichloria mitochondrii IricVA, Candidatus Midichloria mitochondrii str. IricVA, Candidatus Midichloria mitochondrii strain IricVA, Ixodes ricinus endosymbiont, Ixodes ricinus endosymbiont 1 (IricES1), Midichloria, Midichloria mitochondrii, Midichloria mitochondrii IricVA, endosymbiont of Ixodes ricinus
Server load: low (12%) [HD]