STRINGSTRING
holC protein (Midichloria mitochondrii) - STRING interaction network
"holC" - DNA polymerase III subunit chi in Midichloria mitochondrii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holCDNA polymerase III subunit chi (104 aa)    
Predicted Functional Partners:
dgt
Deoxyguanosinetriphosphate triphosphohydrolase (382 aa)
         
    0.900
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (144 aa)
         
    0.900
polA
DNA polymerase I (847 aa)
       
    0.883
dnaN
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (377 aa)
         
    0.800
dnaQ
DNA polymerase III subunit epsilon (225 aa)
         
    0.800
dnaX
DNA polymerase III subunits gamma and tau (511 aa)
         
    0.800
midi_00603
Putative DNA polymerase III delta prime subunit DnaC (134 aa)
         
    0.800
dnaE
DNA polymerase III subunit alpha (1120 aa)
         
    0.800
holA
DNA polymerase III subunit delta (349 aa)
         
    0.800
fliL
Flagellar basal body-associated protein FliL (187 aa)
   
          0.640
Your Current Organism:
Midichloria mitochondrii
NCBI taxonomy Id: 696127
Other names: C. Midichloria, C. Midichloria mitochondrii, C. Midichloria mitochondrii IricVA, Candidatus Midichloria, Candidatus Midichloria mitochondrii, Candidatus Midichloria mitochondrii IricVA, Candidatus Midichloria mitochondrii str. IricVA, Candidatus Midichloria mitochondrii strain IricVA, Ixodes ricinus endosymbiont, Ixodes ricinus endosymbiont 1 (IricES1), Midichloria, Midichloria mitochondrii, Midichloria mitochondrii IricVA, endosymbiont of Ixodes ricinus
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