STRINGSTRING
hemD protein (Midichloria mitochondrii) - STRING interaction network
"hemD" - uroporphyrinogen-III synthase in Midichloria mitochondrii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemDuroporphyrinogen-III synthase (232 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (301 aa)
   
  0.985
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (346 aa)
   
 
  0.950
midi_00106
Delta-aminolevulinic acid dehydratase (308 aa)
   
 
  0.912
midi_01094
Smr/mutS family protein (183 aa)
 
          0.882
midi_00067
Peptidase, M48 family (408 aa)
   
          0.642
midi_00497
Outer membrane protein (1005 aa)
   
          0.619
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis (107 aa)
              0.580
holA
DNA polymerase III subunit delta (349 aa)
 
        0.557
hemH
Protoheme ferro-lyase (ferrochelatase); Catalyzes the ferrous insertion into protoporphyrin IX (363 aa)
   
   
  0.520
fabB
3-oxoacyl-[acyl carrier protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (408 aa)
              0.515
Your Current Organism:
Midichloria mitochondrii
NCBI taxonomy Id: 696127
Other names: C. Midichloria, C. Midichloria mitochondrii, C. Midichloria mitochondrii IricVA, Candidatus Midichloria, Candidatus Midichloria mitochondrii, Candidatus Midichloria mitochondrii IricVA, Candidatus Midichloria mitochondrii str. IricVA, Candidatus Midichloria mitochondrii strain IricVA, Ixodes ricinus endosymbiont, Ixodes ricinus endosymbiont 1 (IricES1), Midichloria, Midichloria mitochondrii, Midichloria mitochondrii IricVA, endosymbiont of Ixodes ricinus
Server load: low (9%) [HD]