STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (213 aa)    
Predicted Functional Partners:
rnfE
Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
  
 0.949
AEE96337.1
COGs: COG0648 Endonuclease IV; InterPro IPR012307: IPR001719; KEGG: tpd:Teth39_1081 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SMART: AP endonuclease family 2; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel.
  
 
 0.819
AEE97093.1
Diguanylate cyclase with GAF sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR003018; KEGG: cth:Cthe_1282 diguanylate cyclase with GAF sensor; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
       0.783
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.741
AEE95949.1
PP-loop domain protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232: IPR011063; KEGG: ckr:CKR_2212 hypothetical protein; PFAM: PP-loop domain protein; SPTR: Putative uncharacterized protein; PFAM: NAD synthase; TIGRFAM: conserved hypothetical protein TIGR00268.
 
    0.735
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
  
 0.635
AEE96542.1
PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterPro IPR004013: IPR002008: IPR002054: IPR003583: IPR 003141; KEGG: tte:TTE2516 family X DNA polymerase IV; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein; SPTR: DNA polymerase IV (Family X); manually curated; PFAM: PHP domain.
     
 0.633
rnfG
Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
  
  
 0.593
AEE97095.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dhd:Dhaf_0823 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Putative uncharacterized protein; PFAM: Glycosyl transferases group 1.
       0.545
AEE96065.1
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR001172: IPR012826: IPR007597: IPR001543; KEGG: tte:TTE1429 flagellar motor switch protein; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; SPTR: Chemotaxis protein CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN.
   
   0.538
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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