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pdxA protein (Methylobacter tundripaludum) - STRING interaction network
"pdxA" - 4-hydroxythreonine-4-phosphate dehydrogenase in Methylobacter tundripaludum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (329 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (359 aa)
         
  0.987
ksgA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (282 aa)
 
   
  0.963
pdxJ
Pyridoxine 5’-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5’-phosphate (PNP) and inorganic phosphate (248 aa)
 
     
  0.894
Mettu_1997
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (163 aa)
 
   
  0.883
Mettu_1041
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (359 aa)
   
 
  0.805
Mettu_0901
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (361 aa)
     
   
  0.719
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (367 aa)
         
  0.714
Mettu_1940
Methane monooxygenase; KEGG- tbi-Tbis_0140 oxidoreductase FAD/NAD(P)-binding domain-containing protein; PFAM- Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase FAD-binding region; Ferredoxin (345 aa)
       
    0.714
apaG
KEGG- tgr-Tgr7_2722 ApaG domain protein; HAMAP- Protein ApaG; PFAM- ApaG (125 aa)
   
   
  0.668
Mettu_1417
KEGG- mca-MCA1406 serine--glyoxylate aminotransferase; PFAM- Aminotransferase, class V/Cysteine desulfurase (388 aa)
       
    0.638
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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