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pfp protein (Methylobacter tundripaludum) - STRING interaction network
"pfp" - Pyrophosphate-dependent 6-phosphofructose-1-kinase in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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pfpPyrophosphate-dependent 6-phosphofructose-1-kinase ; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions (409 aa)    
Predicted Functional Partners:
pgi
Phosphohexose isomerase (545 aa)
   
  0.989
eno
2-phosphoglycerate dehydratase ; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (426 aa)
   
   
  0.928
Mettu_3480
Pyruvate-flavodoxin oxidoreductase ; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (1212 aa)
 
     
  0.912
fbp
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 (334 aa)
   
  0.906
Mettu_4341
Pyruvate kinase (484 aa)
   
 
  0.894
Mettu_2431
Pyruvate kinase (481 aa)
   
 
  0.894
tpiA
Triose-phosphate isomerase ; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) (248 aa)
 
 
  0.891
Mettu_1802
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase (500 aa)
       
    0.890
Mettu_2643
Fructose-bisphosphate aldolase, class II (359 aa)
   
 
  0.879
Mettu_3607
Pyruvate kinase (626 aa)
   
 
  0.862
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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