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murA protein (Methylobacter tundripaludum) - STRING interaction network
"murA" - UDP-N-acetylglucosamine enolpyruvyl transferase in Methylobacter tundripaludum
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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murAUDP-N-acetylglucosamine enolpyruvyl transferase ; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (421 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylmuramate dehydrogenase ; Cell wall formation (304 aa)
 
 
  0.999
murD
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase ; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (479 aa)
 
 
  0.978
hisG
ATP phosphoribosyltransferase ; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (209 aa)
 
   
  0.972
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase ; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (349 aa)
 
 
  0.971
glmU
Bifunctional protein GlmU ; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (488 aa)
   
 
  0.965
murC
UDP-N-acetylmuramoyl-L-alanine synthetase ; Cell wall formation (480 aa)
 
   
  0.958
Mettu_1528
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase (538 aa)
 
   
  0.937
Mettu_1278
UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing (393 aa)
   
 
    0.937
mraY
UDP-MurNAc-pentapeptide phosphotransferase ; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (360 aa)
 
   
  0.929
lpxA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase ; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (256 aa)
   
 
  0.922
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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