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infA protein (Methylobacter tundripaludum) - STRING interaction network
"infA" - Translation initiation factor IF-1 in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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infATranslation initiation factor IF-1 ; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex (72 aa)    
Predicted Functional Partners:
rpsM
30S ribosomal protein S13 ; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P- sites (118 aa)
   
  0.998
rpsQ
30S ribosomal protein S17 ; One of the primary rRNA binding proteins, it binds specifically to the 5’-end of 16S ribosomal RNA (87 aa)
 
  0.997
rpsK
30S ribosomal protein S11 ; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (128 aa)
 
  0.996
rpsG
30S ribosomal protein S7 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (156 aa)
 
  0.995
rpsH
30S ribosomal protein S8 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (131 aa)
 
  0.994
rpsS
30S ribosomal protein S19 ; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (90 aa)
 
  0.993
rpsL
30S ribosomal protein S12 ; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (124 aa)
 
  0.992
rpsD
30S ribosomal protein S4 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (206 aa)
 
  0.991
rpsC
30S ribosomal protein S3 ; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (223 aa)
 
  0.990
rpsI
30S ribosomal protein S9 (131 aa)
 
  0.988
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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