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prfB protein (Methylobacter tundripaludum) - STRING interaction network
"prfB" - Peptide chain release factor 2 in Methylobacter tundripaludum
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfBPeptide chain release factor 2 ; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (365 aa)    
Predicted Functional Partners:
rplB
50S ribosomal protein L2 ; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (275 aa)
     
    0.980
rplM
50S ribosomal protein L13 ; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (142 aa)
 
  0.968
rplC
50S ribosomal protein L3 ; One of the primary rRNA binding proteins, it binds directly near the 3’-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (216 aa)
   
  0.960
rpsR
30S ribosomal protein S18 ; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (75 aa)
 
  0.960
rplL
50S ribosomal protein L7/L12 ; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation (122 aa)
   
  0.953
rplK
50S ribosomal protein L11 ; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors (143 aa)
     
  0.946
rplQ
50S ribosomal protein L17 (125 aa)
   
  0.942
rplS
50S ribosomal protein L19 ; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (113 aa)
   
  0.940
lysS
Lysyl-tRNA synthetase (499 aa)
   
 
  0.935
rplA
50S ribosomal protein L1 ; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (231 aa)
     
  0.935
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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