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dxs protein (Methylobacter tundripaludum) - STRING interaction network
"dxs" - 1-deoxyxylulose-5-phosphate synthase in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dxs1-deoxyxylulose-5-phosphate synthase ; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (620 aa)    
Predicted Functional Partners:
dxr
2-C-methyl-D-erythritol 4-phosphate synthase ; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (394 aa)
 
 
  0.993
thiG
Thiazole synthase ; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (325 aa)
     
 
  0.954
Mettu_0750
Geranyltranstransferase (298 aa)
   
  0.936
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase ; Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (315 aa)
 
   
  0.934
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (157 aa)
 
   
  0.921
ispG
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase ; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (405 aa)
 
   
  0.920
pdxJ
Pyridoxine 5’-phosphate synthase ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5’-phosphate (PNP) and inorganic phosphate (248 aa)
         
  0.909
ispD
MEP cytidylyltransferase ; Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (230 aa)
   
   
  0.900
ispE
4-(cytidine-5’-diphospho)-2-C-methyl-D-erythritol kinase ; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (292 aa)
   
   
  0.900
Mettu_3480
Pyruvate-flavodoxin oxidoreductase ; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (1212 aa)
       
    0.880
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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