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apt protein (Methylobacter tundripaludum) - STRING interaction network
"apt" - Adenine phosphoribosyltransferase in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (171 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (528 aa)
   
  0.986
Mettu_0644
TIGRFAM- Adenylosuccinate lyase; KEGG- tgr-Tgr7_1849 adenylosuccinate lyase; PFAM- Adenylosuccinate lyase C-terminal; Fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (454 aa)
   
  0.962
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (488 aa)
   
  0.908
Mettu_3579
PFAM- Phosphoribosyltransferase; KEGG- nhl-Nhal_2865 phosphoribosyltransferase (179 aa)
   
  0.856
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (204 aa)
   
 
  0.856
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family (212 aa)
   
 
  0.854
Mettu_0389
PFAM- Phosphoribosyltransferase; KEGG- afu-AF0239 xanthine-guanine phosphoribosyltransferase (GptA-1) (201 aa)
   
  0.853
purH
Bifunctional purine biosynthesis protein PurH; KEGG- maq-Maqu_3450 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- AICARFT/IMPCHase bienzyme, formylation region; MGS-like; TIGRFAM- AICARFT/IMPCHase bienzyme; HAMAP- Bifunctional purine biosynthesis protein purH; SMART- AICARFT/IMPCHase bienzyme, formylation region (535 aa)
   
 
  0.838
Mettu_3580
Probable S-methyl-5’-thioinosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5’- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5’-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine (242 aa)
   
 
  0.834
Mettu_2494
Adenosine kinase; KEGG- mca-MCA0047 carbohydrate kinase; PFAM- Carbohydrate/purine kinase (310 aa)
     
  0.828
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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